Pattern of antibiotic resistant mastitis in dairy cows

Mastitis is the most common and economically significant disease affecting dairy cattle. A variety of bacteria can be isolated from bovine mastitis cases. and are the most common causes of contagious and environmental clinical mastitis, respectively. Antimicrobial therapy is commonly implemented for mastitis prevention and control. Unfortunately, despite the best possible antimicrobial treatments, failures of bacteriological cure are common, especially for mastitis and antimicrobial resistance (AMR) which is considered to be one of the reasons for low cure rates [1]. Additionally, AMR in bacteria is a public health hazard, and extensive use of antimicrobial is considered a potentially important driver of AMR. Several strains of from mastitis case have been reported to show resistance against multiple antimicrobials such as penicillin-G, gentamicin, streptomycin, ampicillin, ciprofloxacin, oxytetracycline [2]. Beta–lactam antibiotics are frequently used in mastitis therapy and the resistance is due to the production of beta-lactamases and low-affinity penicillin-binding protein, PBP2A [3].